For the Nike Free 5.0+ - Women's, I would recommend using an actual shoe cleaner that you can find at a store, or simply soap and water. I would try to avoid washing them in a washer and using a dryer, because this can damage them over a long period of time. You don't want to wash if there is any leather on the shoe as well. You will want to air dry if possible, and even with an old brush or rag clean the dirt off the shoes.
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